PIK3CA Expression Profiles in Kidney Carcinoma

Tool Box: Similarity Analysis

Select from the Gene Set

  •   41bb pathway[18]
  •   Ace2 pathway[14]
  •   Ach pathway[17]
  •   Actiny pathway[21]
  •   Agpcr pathway[14]
  •   Agr pathway[37]
  •   Ahsp pathway[14]
  •   Akap13 pathway[13]
  •   Akap95 pathway[13]
  •   Akapcentrosome pathway[16]
  •   Akt pathway[23]
  •   Alk pathway[38]
  •   Ami pathway[21]
  •   Arap pathway[19]
  •   Arenrf2 pathway[14]
  •   Arf pathway[18]
  •   Asbcell pathway[13]
  •   At1r pathway[37]
  •   Atm pathway[21]
  •   Atrbrca pathway[22]
  •   Bad pathway[27]
  •   Barr mapk pathway[13]
  •   Barrestin pathway[11]
  •   Barrestin src pathway[16]
  •   Bcellsurvival pathway[17]
  •   Bcr pathway[38]
  •   Biopeptides pathway[46]
  •   Blymphocyte pathway[12]
  •   Cacam pathway[17]
  •   Calcineurin pathway[22]
  •   Cardiacegf pathway[19]
  •   Carm er pathway[36]
  •   Carm1 pathway[14]
  •   Caspase pathway[24]
  •   Cbl pathway[14]
  •   Ccr3 pathway[24]
  •   Ccr5 pathway[21]
  •   Cd40 pathway[16]
  •   Cdc42rac pathway[17]
  •   Cdk5 pathway[12]
  •   Cdmac pathway[17]
  •   Cell2cell pathway[15]
  •   Cellcycle pathway[24]
  •   Ceramide pathway[23]
  •   Cftr pathway[13]
  •   Chemical pathway[23]
  •   Chrebp2 pathway[43]
  •   Ck1 pathway[18]
  •   Classic pathway[15]
  •   Comp pathway[20]
  •   Creb pathway[28]
  •   Csk pathway[25]
  •   Ctcf pathway[24]
  •   Ctl pathway[16]
  •   Ctla4 pathway[22]
  •   Cxcr4 pathway[25]
  •   Cytokine pathway[23]
  •   D4gdi pathway[14]
  •   Dc pathway[23]
  •   Death pathway[34]
  •   Dnafragment pathway[11]
  •   Dream pathway[15]
  •   Ecm pathway[25]
  •   Edg1 pathway[28]
  •   Egf pathway[32]
  •   Egfr smrte pathway[12]
  •   Eif pathway[17]
  •   Eif2 pathway[12]
  •   Eif4 pathway[25]
  •   Epha4 pathway[11]
  •   Epo pathway[20]
  •   Eponfkb pathway[12]
  •   Erk pathway[29]
  •   Erk5 pathway[19]
  •   Eryth pathway[16]
  •   Etc pathway[13]
  •   Ets pathway[19]
  •   Extrinsic pathway[14]
  •   Fas pathway[31]
  •   Fcer1 pathway[42]
  •   Feeder pathway[10]
  •   Fibrinolysis pathway[13]
  •   Fmlp pathway[40]
  •   Free pathway[11]
  •   G1 pathway[29]
  •   G2 pathway[25]
  •   Gaba pathway[11]
  •   Gata3 pathway[17]
  •   Gcr pathway[23]
  •   Gh pathway[29]
  •   Gleevec pathway[24]
  •   Glycolysis pathway[11]
  •   Gpcr pathway[38]
  •   Granulocytes pathway[15]
  •   Gsk3 pathway[28]
  •   Hcmv pathway[18]
  •   Hdac pathway[33]
  •   Her2 pathway[23]
  •   Hif pathway[16]
  •   Hivnef pathway[59]
  •   Hsp27 pathway[16]
  •   Igf1 pathway[22]
  •   Igf1mtor pathway[21]
  •   Igf1r pathway[24]
  •   Il10 pathway[18]
  •   Il12 pathway[24]
  •   Il17 pathway[18]
  •   Il1r pathway[34]
  •   Il2 pathway[23]
  •   Il22bp pathway[17]
  •   Il2rb pathway[39]
  •   Il3 pathway[16]
  •   Il4 pathway[12]
  •   Il5 pathway[11]
  •   Il6 pathway[23]
  •   Il7 pathway[18]
  •   Inflam pathway[30]
  •   Insulin pathway[23]
  •   Integrin pathway[39]
  •   Intrinsic pathway[24]
  •   Keratinocyte pathway[47]
  •   Kreb pathway[9]
  •   Lair pathway[18]
  •   Lectin pathway[13]
  •   Leptin pathway[12]
  •   Longevity pathway[16]
  •   Lym pathway[12]
  •   Mal pathway[20]
  •   Mapk pathway[88]
  •   Mcalpain pathway[26]
  •   Mcm pathway[19]
  •   Mef2d pathway[24]
  •   Met pathway[38]
  •   Mitochondria pathway[22]
  •   Monocyte pathway[12]
  •   Mpr pathway[35]
  •   Mta3 pathway[20]
  •   Mtor pathway[24]
  •   Myosin pathway[32]
  •   Ndkdynamin pathway[22]
  •   Neurotransmitters pathway[7]
  •   Nfat pathway[57]
  •   Nfkb pathway[24]
  •   Ngf pathway[19]
  •   Nkcells pathway[21]
  •   Nkt pathway[30]
  •   No1 pathway[34]
  •   No2il12 pathway[18]
  •   Nos1 pathway[25]
  •   Nthi pathway[25]
  •   Nuclearrs pathway[16]
  •   P27 pathway[14]
  •   P35alzheimers pathway[12]
  •   P38mapk pathway[41]
  •   P53 pathway[17]
  •   P53hypoxia pathway[24]
  •   Par1 pathway[38]
  •   Parkin pathway[14]
  •   Pdgf pathway[33]
  •   Pgc1a pathway[27]
  •   Pitx2 pathway[16]
  •   Plateletapp pathway[15]
  •   Plce pathway[13]
  •   Pml pathway[18]
  •   Ppara pathway[59]
  •   Proteasome pathway[29]
  •   Ps1 pathway[15]
  •   Ptc1 pathway[12]
  •   Ptdins pathway[24]
  •   Pten pathway[19]
  •   Pyk2 pathway[32]
  •   Rab pathway[13]
  •   Rac1 pathway[24]
  •   Raccycd pathway[27]
  •   Rankl pathway[15]
  •   Ranms pathway[11]
  •   Rarrxr pathway[16]
  •   Ras pathway[24]
  •   Rb pathway[14]
  •   Rela pathway[17]
  •   Rho pathway[33]
  •   Rna pathway[11]
  •   Salmonella pathway[14]
  •   Sars pathway[11]
  •   Set pathway[12]
  •   Shh pathway[17]
  •   Skp2e2f pathway[11]
  •   Sodd pathway[11]
  •   Sppa pathway[23]
  •   Spry pathway[19]
  •   Srcrptp pathway[12]
  •   Stathmin pathway[20]
  •   Stem pathway[16]
  •   Stress pathway[26]
  •   Tall1 pathway[16]
  •   Tcapoptosis pathway[12]
  •   Tcr pathway[50]
  •   Tcra pathway[14]
  •   Tcytotoxic pathway[15]
  •   Tel pathway[19]
  •   Tff pathway[22]
  •   Tgfb pathway[20]
  •   Th1th2 pathway[20]
  •   Thelper pathway[15]
  •   Tid pathway[20]
  •   Tnfr1 pathway[30]
  •   Tnfr2 pathway[19]
  •   Tob1 pathway[22]
  •   Toll pathway[38]
  •   Tpo pathway[25]
  •   Trka pathway[13]
  •   Ucalpain pathway[19]
  •   Vdr pathway[13]
  •   Vegf pathway[30]
  •   Vip pathway[30]
  •   Vitcb pathway[12]
  •   Wnt pathway[27]
  •   Abc transporters[45]
  •   Acute myeloid leukemia[61]
  •   Adherens junction[76]
  •   Adipocytokine signaling pathway[68]
  •   Alanine aspartate and glutamate metabolism[33]
  •   Aldosterone regulated sodium reabsorption[43]
  •   Allograft rejection[39]
  •   Alpha linolenic acid metabolism[20]
  •   Alzheimers disease[170]
  •   Amino sugar and nucleotide sugar metabolism[45]
  •   Aminoacyl trna biosynthesis[42]
  •   Amyotrophic lateral sclerosis als[54]
  •   Antigen processing and presentation[90]
  •   Apoptosis[89]
  •   Arachidonic acid metabolism[59]
  •   Arginine and proline metabolism[55]
  •   Arrhythmogenic right ventricular cardiomyopathy arvc[77]
  •   Ascorbate and aldarate metabolism[26]
  •   Asthma[31]
  •   Autoimmune thyroid disease[54]
  •   Axon guidance[130]
  •   B cell receptor signaling pathway[76]
  •   Basal cell carcinoma[56]
  •   Basal transcription factors[37]
  •   Base excision repair[36]
  •   Beta alanine metabolism[23]
  •   Biosynthesis of unsaturated fatty acids[23]
  •   Bladder cancer[43]
  •   Butanoate metabolism[35]
  •   Calcium signaling pathway[179]
  •   Cardiac muscle contraction[81]
  •   Cell adhesion molecules cams[135]
  •   Cell cycle[129]
  •   Chemokine signaling pathway[191]
  •   Chronic myeloid leukemia[74]
  •   Circadian rhythm mammal[14]
  •   Citrate cycle tca cycle[33]
  •   Colorectal cancer[63]
  •   Complement and coagulation cascades[70]
  •   Cysteine and methionine metabolism[35]
  •   Cytokine cytokine receptor interaction[268]
  •   Cytosolic dna sensing pathway[57]
  •   Dilated cardiomyopathy[93]
  •   Dna replication[37]
  •   Dorso ventral axis formation[26]
  •   Drug metabolism cytochrome p450[73]
  •   Drug metabolism other enzymes[52]
  •   Ecm receptor interaction[85]
  •   Endocytosis[184]
  •   Endometrial cancer[53]
  •   Epithelial cell signaling in helicobacter pylori infection[69]
  •   Erbb signaling pathway[88]
  •   Ether lipid metabolism[34]
  •   Fatty acid metabolism[43]
  •   Fc epsilon ri signaling pathway[80]
  •   Fc gamma r mediated phagocytosis[98]
  •   Focal adhesion[202]
  •   Folate biosynthesis[12]
  •   Fructose and mannose metabolism[35]
  •   Galactose metabolism[27]
  •   Gap junction[91]
  •   Glioma[66]
  •   Glutathione metabolism[51]
  •   Glycerolipid metabolism[50]
  •   Glycerophospholipid metabolism[78]
  •   Glycine serine and threonine metabolism[32]
  •   Glycolysis gluconeogenesis[63]
  •   Glycosaminoglycan biosynthesis chondroitin sulfate[23]
  •   Glycosaminoglycan biosynthesis heparan sulfate[27]
  •   Glycosaminoglycan biosynthesis keratan sulfate[16]
  •   Glycosaminoglycan degradation[22]
  •   Glycosphingolipid biosynthesis ganglio series[16]
  •   Glycosphingolipid biosynthesis globo series[15]
  •   Glycosphingolipid biosynthesis lacto and neolacto series[27]
  •   Glycosylphosphatidylinositol gpi anchor biosynthesis[26]
  •   Glyoxylate and dicarboxylate metabolism[17]
  •   Gnrh signaling pathway[102]
  •   Graft versus host disease[43]
  •   Hedgehog signaling pathway[57]
  •   Hematopoietic cell lineage[89]
  •   Histidine metabolism[30]
  •   Homologous recombination[29]
  •   Huntingtons disease[186]
  •   Hypertrophic cardiomyopathy hcm[86]
  •   Inositol phosphate metabolism[55]
  •   Insulin signaling pathway[138]
  •   Intestinal immune network for iga production[49]
  •   Jak stat signaling pathway[156]
  •   Leishmania infection[73]
  •   Leukocyte transendothelial migration[119]
  •   Limonene and pinene degradation[11]
  •   Linoleic acid metabolism[30]
  •   Long term depression[71]
  •   Long term potentiation[71]
  •   Lysine degradation[45]
  •   Lysosome[122]
  •   Mapk signaling pathway[268]
  •   Maturity onset diabetes of the young[26]
  •   Melanogenesis[103]
  •   Melanoma[72]
  •   Metabolism of xenobiotics by cytochrome p450[71]
  •   Mismatch repair[24]
  •   Mtor signaling pathway[53]
  •   N glycan biosynthesis[47]
  •   Natural killer cell mediated cytotoxicity[138]
  •   Neuroactive ligand receptor interaction[273]
  •   Neurotrophin signaling pathway[127]
  •   Nicotinate and nicotinamide metabolism[25]
  •   Nitrogen metabolism[24]
  •   Nod like receptor signaling pathway[63]
  •   Non homologous end joining[15]
  •   Non small cell lung cancer[55]
  •   Notch signaling pathway[48]
  •   Nucleotide excision repair[45]
  •   O glycan biosynthesis[31]
  •   Olfactory transduction[390]
  •   One carbon pool by folate[18]
  •   Oocyte meiosis[115]
  •   Other glycan degradation[17]
  •   Oxidative phosphorylation[136]
  •   P53 signaling pathway[70]
  •   Pancreatic cancer[71]
  •   Pantothenate and coa biosynthesis[17]
  •   Parkinsons disease[134]
  •   Pathogenic escherichia coli infection[60]
  •   Pathways in cancer[329]
  •   Pentose and glucuronate interconversions[29]
  •   Pentose phosphate pathway[28]
  •   Peroxisome[79]
  •   Phenylalanine metabolism[19]
  •   Phosphatidylinositol signaling system[77]
  •   Porphyrin and chlorophyll metabolism[42]
  •   Ppar signaling pathway[70]
  •   Primary bile acid biosynthesis[17]
  •   Primary immunodeficiency[36]
  •   Prion diseases[36]
  •   Progesterone mediated oocyte maturation[87]
  •   Propanoate metabolism[34]
  •   Prostate cancer[90]
  •   Proteasome[49]
  •   Protein export[25]
  •   Proximal tubule bicarbonate reclamation[24]
  •   Purine metabolism[160]
  •   Pyrimidine metabolism[99]
  •   Pyruvate metabolism[41]
  •   Regulation of actin cytoskeleton[217]
  •   Regulation of autophagy[36]
  •   Renal cell carcinoma[71]
  •   Renin angiotensin system[18]
  •   Retinol metabolism[65]
  •   Riboflavin metabolism[17]
  •   Ribosome[89]
  •   Rig i like receptor signaling pathway[72]
  •   Rna degradation[60]
  •   Rna polymerase[30]
  •   Selenoamino acid metabolism[27]
  •   Small cell lung cancer[85]
  •   Snare interactions in vesicular transport[39]
  •   Sphingolipid metabolism[41]
  •   Spliceosome[129]
  •   Starch and sucrose metabolism[53]
  •   Steroid biosynthesis[18]
  •   Steroid hormone biosynthesis[56]
  •   Sulfur metabolism[14]
  •   Systemic lupus erythematosus[141]
  •   T cell receptor signaling pathway[109]
  •   Taste transduction[53]
  •   Taurine and hypotaurine metabolism[11]
  •   Terpenoid backbone biosynthesis[16]
  •   Tgf beta signaling pathway[87]
  •   Thyroid cancer[30]
  •   Tight junction[135]
  •   Toll like receptor signaling pathway[103]
  •   Tryptophan metabolism[41]
  •   Type i diabetes mellitus[45]
  •   Type ii diabetes mellitus[48]
  •   Tyrosine metabolism[43]
  •   Ubiquitin mediated proteolysis[139]
  •   Valine leucine and isoleucine biosynthesis[12]
  •   Valine leucine and isoleucine degradation[45]
  •   Vascular smooth muscle contraction[116]
  •   Vasopressin regulated water reabsorption[45]
  •   Vegf signaling pathway[77]
  •   Vibrio cholerae infection[57]
  •   Viral myocarditis[74]
  •   Wnt signaling pathway[152]
  •   3 utr mediated translational regulation[177]
  •   A tetrasaccharide linker sequence is required for gag synthesis[26]
  •   Abacavir transport and metabolism[11]
  •   Abc family proteins mediated transport[35]
  •   Abca transporters in lipid homeostasis[19]
  •   Abortive elongation of hiv1 transcript in the absence of tat[24]
  •   Acetylcholine binding and downstream events[17]
  •   Acetylcholine neurotransmitter release cycle[11]
  •   Activated ampk stimulates fatty acid oxidation in muscle[20]
  •   Activated notch1 transmits signal to the nucleus[28]
  •   Activated point mutants of fgfr2[17]
  •   Activated tak1 mediates p38 mapk activation[19]
  •   Activated tlr4 signalling[94]
  •   Activation of atr in response to replication stress[39]
  •   Activation of bh3 only proteins[18]
  •   Activation of chaperone genes by atf6 alpha[12]
  •   Activation of chaperone genes by xbp1s[47]
  •   Activation of chaperones by atf6 alpha[14]
  •   Activation of genes by atf4[27]
  •   Activation of irf3 irf7 mediated by tbk1 ikk epsilon[15]
  •   Activation of kainate receptors upon glutamate binding[32]
  •   Activation of nf kappab in b cells[65]
  •   Activation of nmda receptor upon glutamate binding and postsynaptic events[38]
  •   Activation of rac[15]
  •   Activation of the ap1 family of transcription factors[11]
  •   Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s[85]
  •   Activation of the pre replicative complex[32]
  •   Acyl chain remodelling of pc[23]
  •   Acyl chain remodelling of pe[22]
  •   Acyl chain remodelling of pg[17]
  •   Acyl chain remodelling of pi[16]
  •   Acyl chain remodelling of ps[16]
  •   Adaptive immune system[540]
  •   Adenylate cyclase activating pathway[11]
  •   Adenylate cyclase inhibitory pathway[14]
  •   Adherens junctions interactions[28]
  •   Adp signalling through p2ry1[26]
  •   Adp signalling through p2ry12[22]
  •   Advanced glycosylation endproduct receptor signaling[14]
  •   Akt phosphorylates targets in the cytosol[13]
  •   Alpha linolenic acid ala metabolism[13]
  •   Amine compound slc transporters[28]
  •   Amine derived hormones[16]
  •   Amine ligand binding receptors[39]
  •   Amino acid and oligopeptide slc transporters[50]
  •   Amino acid synthesis and interconversion transamination[18]
  •   Amino acid transport across the plasma membrane[32]
  •   Amyloids[84]
  •   Androgen biosynthesis[11]
  •   Antigen activates b cell receptor leading to generation of second messengers[30]
  •   Antigen presentation folding assembly and peptide loading of class i mhc[22]
  •   Antigen processing cross presentation[77]
  •   Antigen processing ubiquitination proteasome degradation[213]
  •   Antiviral mechanism by ifn stimulated genes[67]
  •   Apc c cdc20 mediated degradation of cyclin b[27]
  •   Apc c cdc20 mediated degradation of mitotic proteins[74]
  •   Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1[73]
  •   Apc cdc20 mediated degradation of nek2a[29]
  •   Apobec3g mediated resistance to hiv1 infection[13]
  •   Apoptosis[149]
  •   Apoptosis induced dna fragmentation[14]
  •   Apoptotic cleavage of cell adhesion proteins[13]
  •   Apoptotic cleavage of cellular proteins[41]
  •   Apoptotic execution phase[55]
  •   Aquaporin mediated transport[52]
  •   Arms mediated activation[18]
  •   Asparagine n linked glycosylation[82]
  •   Assembly of the pre replicative complex[66]
  •   Association of licensing factors with the pre replicative complex[15]
  •   Association of tric cct with target proteins during biosynthesis[28]
  •   Autodegradation of cdh1 by cdh1 apc c[65]
  •   Autodegradation of the e3 ubiquitin ligase cop1[52]
  •   Axon guidance[252]
  •   Base excision repair[20]
  •   Base free sugar phosphate removal via the single nucleotide replacement pathway[11]
  •   Basigin interactions[31]
  •   Beta defensins[43]
  •   Bile acid and bile salt metabolism[28]
  •   Bile salt and organic anion slc transporters[12]
  •   Binding and entry of hiv virion[11]
  •   Biological oxidations[140]
  •   Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein[30]
  •   Bmal1 clock npas2 activates circadian expression[37]
  •   Botulinum neurotoxicity[20]
  •   Branched chain amino acid catabolism[18]
  •   Ca dependent events[31]
  •   Calnexin calreticulin cycle[12]
  •   Caspase mediated cleavage of cytoskeletal proteins[14]
  •   Cd28 co stimulation[33]
  •   Cd28 dependent pi3k akt signaling[23]
  •   Cd28 dependent vav1 pathway[12]
  •   Cdc6 association with the orc origin complex[12]
  •   Cdk mediated phosphorylation and removal of cdc6[49]
  •   Cdt1 association with the cdc6 orc origin complex[57]
  •   Cell cell communication[121]
  •   Cell cell junction organization[57]
  •   Cell cycle[422]
  •   Cell cycle checkpoints[125]
  •   Cell cycle mitotic[326]
  •   Cell death signalling via nrage nrif and nade[61]
  •   Cell extracellular matrix interactions[15]
  •   Cell junction organization[79]
  •   Cell surface interactions at the vascular wall[92]
  •   Cgmp effects[20]
  •   Chemokine receptors bind chemokines[58]
  •   Cholesterol biosynthesis[25]
  •   Chondroitin sulfate biosynthesis[22]
  •   Chondroitin sulfate dermatan sulfate metabolism[50]
  •   Chromosome maintenance[123]
  •   Chylomicron mediated lipid transport[17]
  •   Circadian clock[54]
  •   Circadian repression of expression by rev erba[24]
  •   Citric acid cycle tca cycle[27]
  •   Class a1 rhodopsin like receptors[306]
  •   Class b 2 secretin family receptors[89]
  •   Class c 3 metabotropic glutamate pheromone receptors[16]
  •   Class i mhc mediated antigen processing presentation[252]
  •   Cleavage of growing transcript in the termination region [45]
  •   Collagen formation[59]
  •   Common pathway[15]
  •   Complement cascade[33]
  •   Conversion from apc c cdc20 to apc c cdh1 in late anaphase[23]
  •   Copi mediated transport[11]
  •   Costimulation by the cd28 family[64]
  •   Creation of c4 and c2 activators[11]
  •   Creb phosphorylation through the activation of camkii[16]
  •   Creb phosphorylation through the activation of ras[28]
  •   Crmps in sema3a signaling[15]
  •   Cross presentation of soluble exogenous antigens endosomes[49]
  •   Cs ds degradation[13]
  •   Ctla4 inhibitory signaling[22]
  •   Ctnnb1 phosphorylation cascade[17]
  •   Cyclin a b1 associated events during g2 m transition[16]
  •   Cyclin e associated events during g1 s transition [66]
  •   Cytochrome p450 arranged by substrate type[52]
  •   Cytokine signaling in immune system[271]
  •   Cytosolic sulfonation of small molecules[15]
  •   Cytosolic trna aminoacylation[25]
  •   Dag and ip3 signaling[33]
  •   Darpp 32 events[26]
  •   Dcc mediated attractive signaling[14]
  •   Deadenylation dependent mrna decay[49]
  •   Deadenylation of mrna[23]
  •   Defensins[52]
  •   Degradation of the extracellular matrix[30]
  •   Deposition of new cenpa containing nucleosomes at the centromere[65]
  •   Destabilization of mrna by auf1 hnrnp d0[54]
  •   Destabilization of mrna by brf1[18]
  •   Destabilization of mrna by ksrp[18]
  •   Destabilization of mrna by tristetraprolin ttp[18]
  •   Developmental biology[397]
  •   Diabetes pathways[134]
  •   Digestion of dietary carbohydrate[13]
  •   Dna repair[113]
  •   Dna replication[193]
  •   Dna strand elongation[31]
  •   Dopamine neurotransmitter release cycle[12]
  •   Double strand break repair[25]
  •   Downregulation of erbb2 erbb3 signaling[13]
  •   Downregulation of smad2 3 smad4 transcriptional activity[21]
  •   Downregulation of tgf beta receptor signaling[24]
  •   Downstream signal transduction[96]
  •   Downstream signaling events of b cell receptor bcr[98]
  •   Downstream signaling of activated fgfr[101]
  •   Downstream tcr signaling[38]
  •   Dscam interactions[12]
  •   E2f enabled inhibition of pre replication complex formation[11]
  •   E2f mediated regulation of dna replication[36]
  •   Early phase of hiv life cycle[22]
  •   Effects of pip2 hydrolysis[26]
  •   Egfr downregulation[26]
  •   Eicosanoid ligand binding receptors[17]
  •   Elevation of cytosolic ca2 levels[11]
  •   Elongation arrest and recovery[33]
  •   Endogenous sterols[16]
  •   Endosomal sorting complex required for transport escrt[28]
  •   Endosomal vacuolar pathway[10]
  •   Energy dependent regulation of mtor by lkb1 ampk[19]
  •   Enos activation and regulation[21]
  •   Er phagosome pathway[62]
  •   Erk mapk targets[22]
  •   Erks are inactivated[13]
  •   Ethanol oxidation[11]
  •   Extension of telomeres[28]
  •   Extracellular matrix organization[88]
  •   Extrinsic pathway for apoptosis[14]
  •   Facilitative na independent glucose transporters[13]
  •   Factors involved in megakaryocyte development and platelet production[133]
  •   Fanconi anemia pathway[26]
  •   Fatty acid triacylglycerol and ketone body metabolism[169]
  •   Fatty acyl coa biosynthesis[19]
  •   Fgfr ligand binding and activation[23]
  •   Fgfr1 ligand binding and activation[15]
  •   Fgfr2c ligand binding and activation[13]
  •   Fgfr4 ligand binding and activation[13]
  •   Formation of atp by chemiosmotic coupling[17]
  •   Formation of fibrin clot clotting cascade[33]
  •   Formation of incision complex in gg ner[24]
  •   Formation of rna pol ii elongation complex [46]
  •   Formation of the hiv1 early elongation complex[35]
  •   Formation of the ternary complex and subsequently the 43s complex[75]
  •   Formation of transcription coupled ner tc ner repair complex[31]
  •   Formation of tubulin folding intermediates by cct tric[23]
  •   Frs2 mediated cascade[37]
  •   G alpha i signalling events[196]
  •   G alpha q signalling events[185]
  •   G alpha s signalling events[122]
  •   G alpha z signalling events[45]
  •   G alpha1213 signalling events[75]
  •   G beta gamma signalling through pi3kgamma[26]
  •   G beta gamma signalling through plc beta[21]
  •   G protein activation[28]
  •   G protein beta gamma signalling[29]
  •   G0 and early g1[26]
  •   G1 phase[39]
  •   G1 s specific transcription[20]
  •   G1 s transition[113]
  •   G2 m checkpoints[46]
  •   G2 m dna damage checkpoint[13]
  •   Gab1 signalosome[39]
  •   Gaba a receptor activation[13]
  •   Gaba b receptor activation[39]
  •   Gaba receptor activation[53]
  •   Gaba synthesis release reuptake and degradation[18]
  •   Gamma carboxylation transport and amino terminal cleavage of proteins[12]
  •   Gap junction assembly[19]
  •   Gap junction degradation[11]
  •   Gap junction trafficking[28]
  •   Gastrin creb signalling pathway via pkc and mapk[206]
  •   Generation of second messenger molecules[28]
  •   Generic transcription pathway[353]
  •   Global genomic ner gg ner[36]
  •   Glucagon signaling in metabolic regulation[35]
  •   Glucagon type ligand receptors[34]
  •   Gluconeogenesis[35]
  •   Glucose metabolism[70]
  •   Glucose transport[39]
  •   Glucuronidation[19]
  •   Glutamate neurotransmitter release cycle[16]
  •   Glutathione conjugation[24]
  •   Glycerophospholipid biosynthesis[83]
  •   Glycogen breakdown glycogenolysis[19]
  •   Glycolysis[30]
  •   Glycoprotein hormones[13]
  •   Glycosaminoglycan metabolism[112]
  •   Glycosphingolipid metabolism[39]
  •   Golgi associated vesicle biogenesis[54]
  •   Gpcr downstream signaling[806]
  •   Gpcr ligand binding[409]
  •   Gpvi mediated activation cascade[32]
  •   Grb2 events in erbb2 signaling[23]
  •   Grb2 sos provides linkage to mapk signaling for intergrins [16]
  •   Growth hormone receptor signaling[25]
  •   Hdl mediated lipid transport[16]
  •   Hemostasis[467]
  •   Heparan sulfate heparin hs gag metabolism[53]
  •   Highly calcium permeable postsynaptic nicotinic acetylcholine receptors[14]
  •   Hiv infection[208]
  •   Hiv life cycle[126]
  •   Homologous recombination repair of replication independent double strand breaks[18]
  •   Hormone ligand binding receptors[11]
  •   Hormone sensitive lipase hsl mediated triacylglycerol hydrolysis[14]
  •   Host interactions of hiv factors[133]
  •   Hs gag biosynthesis[32]
  •   Hs gag degradation[21]
  •   Hyaluronan metabolism[15]
  •   Hyaluronan uptake and degradation[11]
  •   Ikk complex recruitment mediated by rip1[11]
  •   Il 2 signaling[42]
  •   Il 3 5 and gm csf signaling[44]
  •   Il 6 signaling[12]
  •   Il 7 signaling[12]
  •   Il receptor shc signaling[28]
  •   Il1 signaling[40]
  •   Immune system[934]
  •   Immunoregulatory interactions between a lymphoid and a non lymphoid cell[71]
  •   Incretin synthesis secretion and inactivation[23]
  •   Inflammasomes[18]
  •   Influenza life cycle[204]
  •   Influenza viral rna transcription and replication[170]
  •   Inhibition of insulin secretion by adrenaline noradrenaline[26]
  •   Inhibition of replication initiation of damaged dna by rb1 e2f1[14]
  •   Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components[25]
  •   Inhibition of voltage gated ca2 channels via gbeta gamma subunits[26]
  •   Initial triggering of complement[17]
  •   Innate immune system[280]
  •   Insulin receptor recycling[24]
  •   Insulin receptor signalling cascade[88]
  •   Insulin synthesis and processing[22]
  •   Integration of energy metabolism[121]
  •   Integration of provirus[17]
  •   Integrin alphaiib beta3 signaling[28]
  •   Integrin cell surface interactions[80]
  •   Interaction between l1 and ankyrins[24]
  •   Interactions of vpr with host cellular proteins[34]
  •   Interferon alpha beta signaling[65]
  •   Interferon gamma signaling[64]
  •   Interferon signaling[160]
  •   Intrinsic pathway[18]
  •   Intrinsic pathway for apoptosis[31]
  •   Inwardly rectifying k channels[32]
  •   Ion channel transport[56]
  •   Ion transport by p type atpases[35]
  •   Ionotropic activity of kainate receptors[12]
  •   Irak1 recruits ikk complex[11]
  •   Irak2 mediated activation of tak1 complex upon tlr7 8 or 9 stimulation[10]
  •   Iron uptake and transport[37]
  •   Jnk c jun kinases phosphorylation and activation mediated by activated human tak1[17]
  •   Keratan sulfate biosynthesis[27]
  •   Keratan sulfate degradation[12]
  •   Keratan sulfate keratin metabolism[31]
  •   Kinesins[25]
  •   L1cam interactions[87]
  •   Lagging strand synthesis[20]
  •   Late phase of hiv life cycle[105]
  •   Latent infection of homo sapiens with mycobacterium tuberculosis[34]
  •   Ligand gated ion channel transport[22]
  •   Lipid digestion mobilization and transport[47]
  •   Lipoprotein metabolism[29]
  •   Loss of nlp from mitotic centrosomes[60]
  •   Lysosome vesicle biogenesis[24]
  •   M g1 transition[82]
  •   Map kinase activation in tlr cascade[51]
  •   Mapk targets nuclear events mediated by map kinases[31]
  •   Meiosis[117]
  •   Meiotic recombination[87]
  •   Meiotic synapsis[74]
  •   Membrane binding and targetting of gag proteins[11]
  •   Membrane trafficking[130]
  •   Metabolism of amino acids and derivatives[201]
  •   Metabolism of carbohydrates[248]
  •   Metabolism of lipids and lipoproteins[479]
  •   Metabolism of mrna[285]
  •   Metabolism of non coding rna[50]
  •   Metabolism of nucleotides[73]
  •   Metabolism of polyamines[16]
  •   Metabolism of porphyrins[15]
  •   Metabolism of proteins[519]
  •   Metabolism of rna[331]
  •   Metabolism of steroid hormones and vitamins a and d[36]
  •   Metabolism of vitamins and cofactors[52]
  •   Metal ion slc transporters[23]
  •   Mhc class ii antigen presentation[92]
  •   Microrna mirna biogenesis[24]
  •   Mitochondrial fatty acid beta oxidation[15]
  •   Mitochondrial protein import[59]
  •   Mitochondrial trna aminoacylation[22]
  •   Mitotic g1 g1 s phases[138]
  •   Mitotic g2 g2 m phases[82]
  •   Mitotic m m g1 phases[173]
  •   Mitotic prometaphase[88]
  •   Mrna 3 end processing[36]
  •   Mrna capping[31]
  •   Mrna decay by 3 to 5 exoribonuclease[12]
  •   Mrna decay by 5 to 3 exoribonuclease[16]
  •   Mrna processing[162]
  •   Mrna splicing[112]
  •   Mrna splicing minor pathway[46]
  •   Mtorc1 mediated signalling[12]
  •   Muscle contraction[49]
  •   Myd88 mal cascade initiated on plasma membrane[84]
  •   Myogenesis[29]
  •   N glycan antennae elongation[15]
  •   N glycan antennae elongation in the medial trans golgi[19]
  •   N glycan trimming in the er and calnexin calreticulin cycle[14]
  •   Na cl dependent neurotransmitter transporters[18]
  •   Ncam signaling for neurite out growth[65]
  •   Ncam1 interactions[40]
  •   Nef mediated downregulation of mhc class i complex cell surface expression[11]
  •   Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters[22]
  •   Negative regulation of fgfr signaling[38]
  •   Negative regulation of the pi3k akt network[10]
  •   Negative regulators of rig i mda5 signaling[32]
  •   Nep ns2 interacts with the cellular export machinery[28]
  •   Nephrin interactions[21]
  •   Netrin1 signaling[42]
  •   Neuronal system[280]
  •   Neurotransmitter receptor binding and downstream transmission in the postsynaptic cell[138]
  •   Neurotransmitter release cycle[35]
  •   Nfkb activation through fadd rip1 pathway mediated by caspase 8 and10[13]
  •   Nfkb and map kinases activation mediated by tlr4 signaling repertoire[73]
  •   Nfkb is activated and signals survival[12]
  •   Ngf signalling via trka from the plasma membrane[138]
  •   Nitric oxide stimulates guanylate cyclase[26]
  •   Nod1 2 signaling pathway[31]
  •   Nonsense mediated decay enhanced by the exon junction complex[177]
  •   Norepinephrine neurotransmitter release cycle[11]
  •   Notch hlh transcription pathway[14]
  •   Notch1 intracellular domain regulates transcription[47]
  •   Nrage signals death through jnk[44]
  •   Nrif signals cell death from the nucleus[16]
  •   Nuclear events kinase and transcription factor activation[25]
  •   Nuclear receptor transcription pathway[50]
  •   Nuclear signaling by erbb4[39]
  •   Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways[47]
  •   Nucleotide excision repair[52]
  •   Nucleotide like purinergic receptors[17]
  •   O linked glycosylation of mucins[60]
  •   Olfactory signaling pathway[329]
  •   Opioid signalling[79]
  •   Opsins[11]
  •   Orc1 removal from chromatin[68]
  •   Organic cation anion zwitterion transport[14]
  •   Other semaphorin interactions[16]
  •   Oxygen dependent proline hydroxylation of hypoxia inducible factor alpha[19]
  •   P130cas linkage to mapk signaling for integrins[16]
  •   P2y receptors[13]
  •   P38mapk events[14]
  •   P53 dependent g1 dna damage response[58]
  •   P53 independent g1 s dna damage checkpoint[52]
  •   P75 ntr receptor mediated signalling[82]
  •   P75ntr recruits signalling complexes[13]
  •   P75ntr signals via nfkb[15]
  •   Packaging of telomere ends[49]
  •   Passive transport by aquaporins[12]
  •   Pd1 signaling[19]
  •   Pecam1 interactions[11]
  •   Peptide chain elongation[154]
  •   Peptide hormone biosynthesis[15]
  •   Peptide ligand binding receptors[189]
  •   Perk regulated gene expression[30]
  •   Peroxisomal lipid metabolism[22]
  •   Phase ii conjugation[71]
  •   Phase1 functionalization of compounds[71]
  •   Phospholipase c mediated cascade[55]
  •   Phospholipid metabolism[199]
  •   Phosphorylation of cd3 and tcr zeta chains[17]
  •   Phosphorylation of the apc c[24]
  •   Pi 3k cascade[57]
  •   Pi metabolism[49]
  •   Pi3k akt activation[39]
  •   Pi3k cascade[72]
  •   Pi3k events in erbb2 signaling[45]
  •   Pi3k events in erbb4 signaling[39]
  •   Pip3 activates akt signaling[30]
  •   Pka mediated phosphorylation of creb[19]
  •   Pkb mediated events[30]
  •   Platelet activation signaling and aggregation[209]
  •   Platelet adhesion to exposed collagen[13]
  •   Platelet aggregation plug formation[37]
  •   Platelet calcium homeostasis[19]
  •   Platelet homeostasis[79]
  •   Platelet sensitization by ldl[17]
  •   Plc beta mediated events[44]
  •   Pol switching[14]
  •   Post chaperonin tubulin folding pathway[20]
  •   Post nmda receptor activation events[34]
  •   Post translational modification synthesis of gpi anchored proteins[27]
  •   Post translational protein modification[189]
  •   Potassium channels[99]
  •   Ppara activates gene expression[105]
  •   Pre notch expression and processing[45]
  •   Pre notch processing in golgi[17]
  •   Pre notch transcription and translation[30]
  •   Prefoldin mediated transfer of substrate to cct tric[29]
  •   Presynaptic nicotinic acetylcholine receptors[13]
  •   Processing of capped intron containing pre mrna[141]
  •   Processing of capped intronless pre mrna[24]
  •   Processing of intronless pre mrnas[15]
  •   Processive synthesis on the lagging strand[16]
  •   Prolactin receptor signaling[15]
  •   Prolonged erk activation events[20]
  •   Prostacyclin signalling through prostacyclin receptor[20]
  •   Prostanoid ligand receptors[11]
  •   Protein folding[54]
  •   Proteolytic cleavage of snare complex proteins[18]
  •   Ptm gamma carboxylation hypusine formation and arylsulfatase activation[28]
  •   Purine catabolism[11]
  •   Purine metabolism[34]
  •   Purine ribonucleoside monophosphate biosynthesis[12]
  •   Purine salvage[14]
  •   Pyrimidine catabolism[13]
  •   Pyrimidine metabolism[25]
  •   Pyruvate metabolism[20]
  •   Pyruvate metabolism and citric acid tca cycle[49]
  •   Raf map kinase cascade[11]
  •   Rap1 signalling[18]
  •   Ras activation uopn ca2 infux through nmda receptor[18]
  •   Receptor ligand binding initiates the second proteolytic cleavage of notch receptor[13]
  •   Recruitment of mitotic centrosome proteins and complexes[67]
  •   Recruitment of numa to mitotic centrosomes[11]
  •   Recycling of bile acids and salts[12]
  •   Recycling pathway of l1[28]
  •   Regulated proteolysis of p75ntr[11]
  •   Regulation of ampk activity via lkb1[16]
  •   Regulation of apoptosis[59]
  •   Regulation of beta cell development[31]
  •   Regulation of complement cascade[15]
  •   Regulation of gene expression in beta cells[21]
  •   Regulation of glucokinase by glucokinase regulatory protein[28]
  •   Regulation of hypoxia inducible factor hif by oxygen[26]
  •   Regulation of ifna signaling[25]
  •   Regulation of ifng signaling[15]
  •   Regulation of insulin like growth factor igf activity by insulin like growth factor binding proteins igfbps[17]
  •   Regulation of insulin secretion[94]
  •   Regulation of insulin secretion by acetylcholine[12]
  •   Regulation of insulin secretion by glucagon like peptide1[44]
  •   Regulation of kit signaling[18]
  •   Regulation of mitotic cell cycle[86]
  •   Regulation of mrna stability by proteins that bind au rich elements[85]
  •   Regulation of ornithine decarboxylase odc[50]
  •   Regulation of pyruvate dehydrogenase pdh complex[14]
  •   Regulation of rheb gtpase activity by ampk[11]
  •   Regulation of signaling by cbl[19]
  •   Regulation of the fanconi anemia pathway[12]
  •   Regulation of water balance by renal aquaporins[45]
  •   Regulatory rna pathways[27]
  •   Removal of the flap intermediate from the c strand[11]
  •   Repair synthesis for gap filling by dna pol in tc ner[15]
  •   Resolution of ap sites via the multiple nucleotide patch replacement pathway[18]
  •   Resolution of ap sites via the single nucleotide replacement pathway[13]
  •   Respiratory electron transport[80]
  •   Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins [99]
  •   Response to elevated platelet cytosolic ca2 [90]
  •   Retrograde neurotrophin signalling[14]
  •   Reversible hydration of carbon dioxide[13]
  •   Rig i mda5 mediated induction of ifn alpha beta pathways[74]
  •   Rip mediated nfkb activation via dai[19]
  •   Rna pol i promoter opening[63]
  •   Rna pol i rna pol iii and mitochondrial transcription[123]
  •   Rna pol i transcription[90]
  •   Rna pol i transcription initiation[26]
  •   Rna pol i transcription termination[23]
  •   Rna pol ii pre transcription events[62]
  •   Rna pol ii transcription[106]
  •   Rna pol ii transcription pre initiation and promoter opening[42]
  •   Rna pol iii chain elongation[18]
  •   Rna pol iii transcription[34]
  •   Rna pol iii transcription initiation from type 2 promoter[24]
  •   Rna pol iii transcription initiation from type 3 promoter[27]
  •   Rna pol iii transcription termination[20]
  •   Role of dcc in regulating apoptosis[11]
  •   Role of second messengers in netrin1 signaling[12]
  •   Rora activates circadian expression[25]
  •   S phase[110]
  •   Scf beta trcp mediated degradation of emi1[52]
  •   Scfskp2 mediated degradation of p27 p21[57]
  •   Sema3a pak dependent axon repulsion[16]
  •   Sema3a plexin repulsion signaling by inhibiting integrin adhesion[14]
  •   Sema4d in semaphorin signaling[33]
  •   Sema4d induced cell migration and growth cone collapse[28]
  •   Semaphorin interactions[69]
  •   Serotonin receptors[13]
  •   Shc mediated cascade[29]
  •   Shc mediated signalling[16]
  •   Shc related events[18]
  •   Shc1 events in egfr signaling[16]
  •   Shc1 events in erbb4 signaling[21]
  •   Signal amplification[32]
  •   Signal attenuation[15]
  •   Signal regulatory protein sirp family interactions[13]
  •   Signal transduction by l1[35]
  •   Signaling by activated point mutants of fgfr1[12]
  •   Signaling by bmp[24]
  •   Signaling by constitutively active egfr[19]
  •   Signaling by egfr in cancer[110]
  •   Signaling by erbb2[102]
  •   Signaling by erbb4[91]
  •   Signaling by fgfr[113]
  •   Signaling by fgfr in disease[128]
  •   Signaling by fgfr mutants[45]
  •   Signaling by fgfr1 fusion mutants[20]
  •   Signaling by fgfr1 mutants[31]
  •   Signaling by fgfr3 mutants[12]
  •   Signaling by gpcr[921]
  •   Signaling by hippo[23]
  •   Signaling by ils[108]
  •   Signaling by insulin receptor[109]
  •   Signaling by nodal[19]
  •   Signaling by notch[104]
  •   Signaling by notch1[71]
  •   Signaling by notch2[13]
  •   Signaling by notch3[13]
  •   Signaling by notch4[13]
  •   Signaling by pdgf[123]
  •   Signaling by rho gtpases[114]
  •   Signaling by robo receptor[31]
  •   Signaling by scf kit[79]
  •   Signaling by tgf beta receptor complex[64]
  •   Signaling by the b cell receptor bcr[127]
  •   Signaling by wnt[66]
  •   Signalling by ngf[218]
  •   Signalling to erks[37]
  •   Signalling to p38 via rit and rin[16]
  •   Signalling to ras[28]
  •   Slbp dependent processing of replication dependent histone pre mrnas[12]
  •   Slc mediated transmembrane transport[242]
  •   Smad2 smad3 smad4 heterotrimer regulates transcription[28]
  •   Smooth muscle contraction[26]
  •   Sos mediated signalling[15]
  •   Sphingolipid de novo biosynthesis[32]
  •   Sphingolipid metabolism[70]
  •   Spry regulation of fgf signaling[15]
  •   Srp dependent cotranslational protein targeting to membrane[180]
  •   Steroid hormones[30]
  •   Striated muscle contraction[28]
  •   Sulfur amino acid metabolism[25]
  •   Synthesis and interconversion of nucleotide di and triphosphates[20]
  •   Synthesis of bile acids and bile salts[20]
  •   Synthesis of bile acids and bile salts via 24 hydroxycholesterol[11]
  •   Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol[16]
  •   Synthesis of dna[93]
  •   Synthesis of glycosylphosphatidylinositol gpi[18]
  •   Synthesis of pa[28]
  •   Synthesis of pc[19]
  •   Synthesis of pe[12]
  •   Synthesis of pips at the early endosome membrane[13]
  •   Synthesis of pips at the golgi membrane[18]
  •   Synthesis of pips at the late endosome membrane[11]
  •   Synthesis of pips at the plasma membrane[32]
  •   Synthesis of substrates in n glycan biosythesis[15]
  •   Synthesis of very long chain fatty acyl coas[15]
  •   Synthesis secretion and deacylation of ghrelin[17]
  •   Synthesis secretion and inactivation of gip[15]
  •   Synthesis secretion and inactivation of glp1[20]
  •   Tak1 activates nfkb by phosphorylation and activation of ikks complex[24]
  •   Tandem pore domain potassium channels[13]
  •   Tca cycle and respiratory electron transport[142]
  •   Tcr signaling[55]
  •   Telomere maintenance[76]
  •   Termination of o glycan biosynthesis[25]
  •   Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation[14]
  •   Tgf beta receptor signaling activates smads[27]
  •   Tgf beta receptor signaling in emt epithelial to mesenchymal transition[17]
  •   The activation of arylsulfatases[13]
  •   The nlrp3 inflammasome[13]
  •   The role of nef in hiv1 replication and disease pathogenesis[29]
  •   Thrombin signalling through proteinase activated receptors pars[33]
  •   Thromboxane signalling through tp receptor[24]
  •   Tie2 signaling[18]
  •   Tight junction interactions[30]
  •   Toll receptor cascades[119]
  •   Traf3 dependent irf activation pathway[15]
  •   Traf6 mediated induction of nfkb and map kinases upon tlr7 8 or 9 activation[78]
  •   Traf6 mediated induction of tak1 complex[15]
  •   Traf6 mediated irf7 activation[31]
  •   Traf6 mediated irf7 activation in tlr7 8 or 9 signaling[11]
  •   Traf6 mediated nfkb activation[22]
  •   Trafficking and processing of endosomal tlr[15]
  •   Trafficking of ampa receptors[29]
  •   Trafficking of glur2 containing ampa receptors[17]
  •   Trans golgi network vesicle budding[61]
  •   Transcription[211]
  •   Transcription coupled ner tc ner[46]
  •   Transcriptional activity of smad2 smad3 smad4 heterotrimer[39]
  •   Transcriptional regulation of white adipocyte differentiation[73]
  •   Transferrin endocytosis and recycling[26]
  •   Translation[223]
  •   Translocation of zap 70 to immunological synapse[15]
  •   Transmembrane transport of small molecules[414]
  •   Transmission across chemical synapses[187]
  •   Transport of glucose and other sugars bile salts and organic acids metal ions and amine compounds[90]
  •   Transport of inorganic cations anions and amino acids oligopeptides[95]
  •   Transport of mature mrna derived from an intronless transcript[34]
  •   Transport of mature transcript to cytoplasm[55]
  •   Transport of organic anions[12]
  •   Transport of ribonucleoproteins into the host nucleus[28]
  •   Transport of vitamins nucleosides and related molecules[32]
  •   Transport to the golgi and subsequent modification[34]
  •   Trif mediated tlr3 signaling[75]
  •   Triglyceride biosynthesis[39]
  •   Trna aminoacylation[43]
  •   Tryptophan catabolism[12]
  •   Unblocking of nmda receptor glutamate binding and activation[16]
  •   Unfolded protein response[81]
  •   Unwinding of dna[12]
  •   Vegf ligand receptor interactions[11]
  •   Vif mediated degradation of apobec3g[53]
  •   Viral messenger rna synthesis[15]
  •   Vitamin b5 pantothenate metabolism[12]
  •   Voltage gated potassium channels[44]
  •   Xenobiotics[17]
  •   Yap1 and wwtr1 taz stimulated gene expression[25]
  •   Zinc transporters[16]
Sample Grouping
1 GSM1134764 patient 1 normal tissue no smoking no obese Par059HG-U133_Plus_2.celpatient: 1tissue: normalsmoking: noobese: nobatch: 2duplicate: no
2 GSM1134766 patient 14 normal tissue yes smoking no obese Par061HG-U133_Plus_2.celpatient: 14tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
3 GSM1134768 patient 16 normal tissue no smoking no obese Par063HG-U133_Plus_2.celpatient: 16tissue: normalsmoking: noobese: nobatch: 2duplicate: no
4 GSM1134770 patient 28 normal tissue no smoking no obese Par065HG-U133_Plus_2.celpatient: 28tissue: normalsmoking: noobese: nobatch: 2duplicate: no
5 GSM1134772 patient 42 normal tissue yes smoking no obese Par067HG-U133_Plus_2.celpatient: 42tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
6 GSM1134774 patient 43 normal tissue no smoking no obese Par069HG-U133_Plus_2.celpatient: 43tissue: normalsmoking: noobese: nobatch: 2duplicate: no
7 GSM1134776 patient 53 normal tissue yes smoking no obese Par071HG-U133_Plus_2.celpatient: 53tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
8 GSM1134778 patient 55 normal tissue yes smoking yes obese Par073HG-U133_Plus_2.celpatient: 55tissue: normalsmoking: yesobese: yesbatch: 2duplicate: no
9 GSM1134780 patient 74 normal tissue yes smoking no obese Par075HG-U133_Plus_2.celpatient: 74tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
10 GSM1134782 patient 92 normal tissue no smoking no obese Par077HG-U133_Plus_2.celpatient: 92tissue: normalsmoking: noobese: nobatch: 2duplicate: no
11 GSM1134784 patient 96 normal tissue no smoking no obese Par079HG-U133_Plus_2.celpatient: 96tissue: normalsmoking: noobese: nobatch: 2duplicate: no
12 GSM1134786 patient 98 normal tissue yes smoking yes obese Par081HG-U133_Plus_2.celpatient: 98tissue: normalsmoking: yesobese: yesbatch: 2duplicate: no
13 GSM1134788 patient 103 normal tissue yes smoking no obese Par083HG-U133_Plus_2.celpatient: 103tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
14 GSM1134790 patient 110 normal tissue yes smoking no obese Par085HG-U133_Plus_2.celpatient: 110tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
15 GSM1134792 patient 121 normal tissue yes smoking yes obese Par087HG-U133_Plus_2.celpatient: 121tissue: normalsmoking: yesobese: yesbatch: 2duplicate: no
16 GSM1134794 patient 129 normal tissue no smoking no obese Par089HG-U133_Plus_2.celpatient: 129tissue: normalsmoking: noobese: nobatch: 2duplicate: no
17 GSM1134796 patient 144 normal tissue yes smoking yes obese Par091HG-U133_Plus_2.celpatient: 144tissue: normalsmoking: yesobese: yesbatch: 2duplicate: no
18 GSM1134798 patient 192 normal tissue no smoking no obese Par093HG-U133_Plus_2.celpatient: 192tissue: normalsmoking: noobese: nobatch: 2duplicate: no
19 GSM1134800 patient 194 normal tissue no smoking no obese Par095HG-U133_Plus_2.celpatient: 194tissue: normalsmoking: noobese: nobatch: 2duplicate: no
20 GSM1134802 patient 205 normal tissue no smoking no obese Par097HG-U133_Plus_2.celpatient: 205tissue: normalsmoking: noobese: nobatch: 2duplicate: no
21 GSM1134805 patient 160 normal tissue no smoking no obese Par100HG-U133_Plus_2.celpatient: 160tissue: normalsmoking: noobese: nobatch: 2duplicate: no
22 GSM1134807 patient 427 normal tissue yes smoking no obese Par102HG-U133_Plus_2.celpatient: 427tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
23 GSM1134809 patient 498 normal tissue no smoking no obese Par104HG-U133_Plus_2.celpatient: 498tissue: normalsmoking: noobese: nobatch: 2duplicate: no
24 GSM1134811 patient 562 normal tissue no smoking no obese Par106HG-U133_Plus_2.celpatient: 562tissue: normalsmoking: noobese: nobatch: 2duplicate: no
25 GSM1134813 patient 652 normal tissue no smoking no obese Par108HG-U133_Plus_2.celpatient: 652tissue: normalsmoking: noobese: nobatch: 2duplicate: no
26 GSM1134815 patient 670 normal tissue yes smoking no obese Par110HG-U133_Plus_2.celpatient: 670tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
27 GSM1134817 patient 705 normal tissue yes smoking yes obese Par112HG-U133_Plus_2.celpatient: 705tissue: normalsmoking: yesobese: yesbatch: 2duplicate: no
28 GSM1134819 patient 712 normal tissue no smoking no obese Par114HG-U133_Plus_2.celpatient: 712tissue: normalsmoking: noobese: nobatch: 2duplicate: no
29 GSM1134821 patient 723 normal tissue no smoking no obese Par116HG-U133_Plus_2.celpatient: 723tissue: normalsmoking: noobese: nobatch: 2duplicate: no
30 GSM1134823 patient 726 normal tissue no smoking no obese Par118HG-U133_Plus_2.celpatient: 726tissue: normalsmoking: noobese: nobatch: 2duplicate: no
31 GSM1134825 patient 739 normal tissue no smoking no obese Par120HG-U133_Plus_2.celpatient: 739tissue: normalsmoking: noobese: nobatch: 2duplicate: no
32 GSM1134827 patient 740 normal tissue yes smoking yes obese Par122HG-U133_Plus_2.celpatient: 740tissue: normalsmoking: yesobese: yesbatch: 2duplicate: no
33 GSM1134829 patient 746 normal tissue yes smoking no obese Par124HG-U133_Plus_2.celpatient: 746tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
34 GSM1134831 patient 829 normal tissue yes smoking no obese Par126HG-U133_Plus_2.celpatient: 829tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
35 GSM1134833 patient 853 normal tissue yes smoking no obese Par128HG-U133_Plus_2.celpatient: 853tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
36 GSM1134835 patient 865 normal tissue yes smoking yes obese Par130HG-U133_Plus_2.celpatient: 865tissue: normalsmoking: yesobese: yesbatch: 2duplicate: no
37 GSM1134837 patient 871 normal tissue yes smoking no obese Par132HG-U133_Plus_2.celpatient: 871tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
38 GSM1134839 patient 1018 normal tissue yes smoking no obese Par134HG-U133_Plus_2.celpatient: 1018tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
39 GSM1134841 patient 1048 normal tissue no smoking no obese Par136HG-U133_Plus_2.celpatient: 1048tissue: normalsmoking: noobese: nobatch: 2duplicate: no
40 GSM1134843 patient 263 normal tissue yes smoking no obese Par138HG-U133_Plus_2.celpatient: 263tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
41 GSM1134845 patient 878 normal tissue yes smoking no obese Par140HG-U133_Plus_2.celpatient: 878tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
42 GSM1134847 patient 888 normal tissue yes smoking no obese Par142HG-U133_Plus_2.celpatient: 888tissue: normalsmoking: yesobese: nobatch: 2duplicate: no
43 GSM1134849 patient 18 normal tissue no smoking no obese Par002U133Plus2.0.CELpatient: 18tissue: normalsmoking: noobese: nobatch: 1duplicate: no
44 GSM1134851 patient 60 normal tissue no smoking yes obese Par004U133Plus2.0.CELpatient: 60tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
45 GSM1134853 patient 69 normal tissue no smoking yes obese Par006U133Plus2.0.CELpatient: 69tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
46 GSM1134855 patient 163 normal tissue no smoking yes obese Par010U133Plus2.0.CELpatient: 163tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
47 GSM1134857 patient 177 normal tissue no smoking yes obese Par012U133Plus2.0.CELpatient: 177tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
48 GSM1134859 patient 181 normal tissue no smoking yes obese Par014U133Plus2.0.CELpatient: 181tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
49 GSM1134861 patient 196 normal tissue no smoking no obese Par016U133Plus2.0.CELpatient: 196tissue: normalsmoking: noobese: nobatch: 1duplicate: no
50 GSM1134863 patient 202 normal tissue no smoking no obese Par018U133Plus2.0.CELpatient: 202tissue: normalsmoking: noobese: nobatch: 1duplicate: no
51 GSM1134865 patient 252 normal tissue no smoking yes obese Par022U133Plus2.0.CELpatient: 252tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
52 GSM1134867 patient 264 normal tissue no smoking yes obese Par024U133Plus2.0.CELpatient: 264tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
53 GSM1134869 patient 275 normal tissue no smoking no obese Par028U133Plus2.0.CELpatient: 275tissue: normalsmoking: noobese: nobatch: 1duplicate: no
54 GSM1134871 patient 363 normal tissue no smoking yes obese Par032U133Plus2.0.CELpatient: 363tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
55 GSM1134873 patient 407 normal tissue no smoking yes obese Par034U133Plus2.0.CELpatient: 407tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
56 GSM1134875 patient 452 normal tissue no smoking no obese Par036U133Plus2.0.CELpatient: 452tissue: normalsmoking: noobese: nobatch: 1duplicate: no
57 GSM1134877 patient 20 normal tissue no smoking yes obese Par038U133Plus2.0.CELpatient: 20tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
58 GSM1134879 patient 41 normal tissue no smoking yes obese Par044U133Plus2.0.CELpatient: 41tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
59 GSM1134881 patient 785 normal tissue no smoking no obese Par046HG-U133_Plus_2.celpatient: 785tissue: normalsmoking: noobese: nobatch: 1duplicate: no
60 GSM1134884 patient 806 normal tissue no smoking no obese Par050HG-U133_Plus_2.celpatient: 806tissue: normalsmoking: noobese: nobatch: 1duplicate: no
61 GSM1134886 patient 521 normal tissue no smoking yes obese Par052HG-U133_Plus_2.celpatient: 521tissue: normalsmoking: noobese: yesbatch: 1duplicate: no
62 GSM1304421 patient 160 normal tissue no smoking no obese Par008U133Plus2.0.CELpatient: 160tissue: normalsmoking: noobese: nobatch: 1duplicate: yes
63 GSM1304423 patient 28 normal tissue no smoking no obese Par042U133Plus2.0.CELpatient: 28tissue: normalsmoking: noobese: nobatch: 1duplicate: yes
1 GSM1134765 patient 1 tumor tissue no smoking no obese Par060HG-U133_Plus_2.celpatient: 1tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
2 GSM1134767 patient 14 tumor tissue yes smoking no obese Par062HG-U133_Plus_2.celpatient: 14tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
3 GSM1134769 patient 16 tumor tissue no smoking no obese Par064HG-U133_Plus_2.celpatient: 16tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
4 GSM1134771 patient 28 tumor tissue no smoking no obese Par066HG-U133_Plus_2.celpatient: 28tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
5 GSM1134773 patient 42 tumor tissue yes smoking no obese Par068HG-U133_Plus_2.celpatient: 42tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
6 GSM1134775 patient 43 tumor tissue no smoking no obese Par070HG-U133_Plus_2.celpatient: 43tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
7 GSM1134777 patient 53 tumor tissue yes smoking no obese Par072HG-U133_Plus_2.celpatient: 53tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
8 GSM1134779 patient 55 tumor tissue yes smoking yes obese Par074HG-U133_Plus_2.celpatient: 55tissue: tumorsmoking: yesobese: yesbatch: 2duplicate: no
9 GSM1134781 patient 74 tumor tissue yes smoking no obese Par076HG-U133_Plus_2.celpatient: 74tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
10 GSM1134783 patient 92 tumor tissue no smoking no obese Par078HG-U133_Plus_2.celpatient: 92tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
11 GSM1134785 patient 96 tumor tissue no smoking no obese Par080HG-U133_Plus_2.celpatient: 96tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
12 GSM1134787 patient 98 tumor tissue yes smoking yes obese Par082HG-U133_Plus_2.celpatient: 98tissue: tumorsmoking: yesobese: yesbatch: 2duplicate: no
13 GSM1134789 patient 103 tumor tissue yes smoking no obese Par084HG-U133_Plus_2.celpatient: 103tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
14 GSM1134791 patient 110 tumor tissue yes smoking no obese Par086HG-U133_Plus_2.celpatient: 110tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
15 GSM1134793 patient 121 tumor tissue yes smoking yes obese Par088HG-U133_Plus_2.celpatient: 121tissue: tumorsmoking: yesobese: yesbatch: 2duplicate: no
16 GSM1134795 patient 129 tumor tissue no smoking no obese Par090HG-U133_Plus_2.celpatient: 129tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
17 GSM1134797 patient 144 tumor tissue yes smoking yes obese Par092HG-U133_Plus_2.celpatient: 144tissue: tumorsmoking: yesobese: yesbatch: 2duplicate: no
18 GSM1134799 patient 192 tumor tissue no smoking no obese Par094HG-U133_Plus_2.celpatient: 192tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
19 GSM1134801 patient 194 tumor tissue no smoking no obese Par096HG-U133_Plus_2.celpatient: 194tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
20 GSM1134803 patient 205 tumor tissue no smoking no obese Par098HG-U133_Plus_2.celpatient: 205tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
21 GSM1134804 patient 160 tumor tissue no smoking no obese Par099HG-U133_Plus_2.celpatient: 160tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
22 GSM1134806 patient 427 tumor tissue yes smoking no obese Par101HG-U133_Plus_2.celpatient: 427tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
23 GSM1134808 patient 498 tumor tissue no smoking no obese Par103HG-U133_Plus_2.celpatient: 498tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
24 GSM1134810 patient 562 tumor tissue no smoking no obese Par105HG-U133_Plus_2.celpatient: 562tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
25 GSM1134812 patient 652 tumor tissue no smoking no obese Par107HG-U133_Plus_2.celpatient: 652tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
26 GSM1134814 patient 670 tumor tissue yes smoking no obese Par109HG-U133_Plus_2.celpatient: 670tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
27 GSM1134816 patient 705 tumor tissue yes smoking yes obese Par111HG-U133_Plus_2.celpatient: 705tissue: tumorsmoking: yesobese: yesbatch: 2duplicate: no
28 GSM1134818 patient 712 tumor tissue no smoking no obese Par113HG-U133_Plus_2.celpatient: 712tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
29 GSM1134820 patient 723 tumor tissue no smoking no obese Par115HG-U133_Plus_2.celpatient: 723tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
30 GSM1134822 patient 726 tumor tissue no smoking no obese Par117HG-U133_Plus_2.celpatient: 726tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
31 GSM1134824 patient 739 tumor tissue no smoking no obese Par119HG-U133_Plus_2.celpatient: 739tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
32 GSM1134826 patient 740 tumor tissue yes smoking yes obese Par121HG-U133_Plus_2.celpatient: 740tissue: tumorsmoking: yesobese: yesbatch: 2duplicate: no
33 GSM1134828 patient 746 tumor tissue yes smoking no obese Par123HG-U133_Plus_2.celpatient: 746tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
34 GSM1134830 patient 829 tumor tissue yes smoking no obese Par125HG-U133_Plus_2.celpatient: 829tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
35 GSM1134832 patient 853 tumor tissue yes smoking no obese Par127HG-U133_Plus_2.celpatient: 853tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
36 GSM1134834 patient 865 tumor tissue yes smoking yes obese Par129HG-U133_Plus_2.celpatient: 865tissue: tumorsmoking: yesobese: yesbatch: 2duplicate: no
37 GSM1134836 patient 871 tumor tissue yes smoking no obese Par131HG-U133_Plus_2.celpatient: 871tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
38 GSM1134838 patient 1018 tumor tissue yes smoking no obese Par133HG-U133_Plus_2.celpatient: 1018tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
39 GSM1134840 patient 1048 tumor tissue no smoking no obese Par135HG-U133_Plus_2.celpatient: 1048tissue: tumorsmoking: noobese: nobatch: 2duplicate: no
40 GSM1134842 patient 263 tumor tissue yes smoking no obese Par137HG-U133_Plus_2.celpatient: 263tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
41 GSM1134844 patient 878 tumor tissue yes smoking no obese Par139HG-U133_Plus_2.celpatient: 878tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
42 GSM1134846 patient 888 tumor tissue yes smoking no obese Par141HG-U133_Plus_2.celpatient: 888tissue: tumorsmoking: yesobese: nobatch: 2duplicate: no
43 GSM1134848 patient 18 tumor tissue no smoking no obese Par001U133Plus2.0.CELpatient: 18tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
44 GSM1134850 patient 60 tumor tissue no smoking yes obese Par003U133Plus2.0.CELpatient: 60tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
45 GSM1134852 patient 69 tumor tissue no smoking yes obese Par005U133Plus2.0.CELpatient: 69tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
46 GSM1134854 patient 163 tumor tissue no smoking yes obese Par009U133Plus2.0.CELpatient: 163tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
47 GSM1134856 patient 177 tumor tissue no smoking yes obese Par011U133Plus2.0.CELpatient: 177tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
48 GSM1134858 patient 181 tumor tissue no smoking yes obese Par013U133Plus2.0.CELpatient: 181tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
49 GSM1134860 patient 196 tumor tissue no smoking no obese Par015U133Plus2.0.CELpatient: 196tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
50 GSM1134862 patient 202 tumor tissue no smoking no obese Par017U133Plus2.0.CELpatient: 202tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
51 GSM1134864 patient 252 tumor tissue no smoking yes obese Par021U133Plus2.0.CELpatient: 252tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
52 GSM1134866 patient 264 tumor tissue no smoking yes obese Par023U133Plus2.0.CELpatient: 264tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
53 GSM1134868 patient 275 tumor tissue no smoking no obese Par027U133Plus2.0.CELpatient: 275tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
54 GSM1134870 patient 363 tumor tissue no smoking yes obese Par031U133Plus2.0.CELpatient: 363tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
55 GSM1134872 patient 407 tumor tissue no smoking yes obese Par033U133Plus2.0.CELpatient: 407tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
56 GSM1134874 patient 452 tumor tissue no smoking no obese Par035U133Plus2.0.CELpatient: 452tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
57 GSM1134876 patient 20 tumor tissue no smoking yes obese Par037U133Plus2.0.CELpatient: 20tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
58 GSM1134878 patient 41 tumor tissue no smoking yes obese Par043U133Plus2.0.CELpatient: 41tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
59 GSM1134880 patient 785 tumor tissue no smoking no obese Par045HG-U133_Plus_2.celpatient: 785tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
60 GSM1134882 patient 799 tumor tissue no smoking no obese Par047HG-U133_Plus_2.celpatient: 799tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
61 GSM1134883 patient 806 tumor tissue no smoking no obese Par049HG-U133_Plus_2.celpatient: 806tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
62 GSM1134885 patient 521 tumor tissue no smoking yes obese Par051HG-U133_Plus_2.celpatient: 521tissue: tumorsmoking: noobese: yesbatch: 1duplicate: no
63 GSM1134887 patient 523 tumor tissue no smoking no obese Par053HG-U133_Plus_2.celpatient: 523tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
64 GSM1134888 patient 559 tumor tissue no smoking no obese Par055HG-U133_Plus_2.celpatient: 559tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
65 GSM1134889 patient 684 tumor tissue no smoking no obese Par057HG-U133_Plus_2.celpatient: 684tissue: tumorsmoking: noobese: nobatch: 1duplicate: no
66 GSM1304420 patient 160 tumor tissue no smoking no obese Par007U133Plus2.0.CELpatient: 160tissue: tumorsmoking: noobese: nobatch: 1duplicate: yes
67 GSM1304422 patient 28 tumor tissue no smoking no obese Par041U133Plus2.0.CELpatient: 28tissue: tumorsmoking: noobese: nobatch: 1duplicate: yes
Gene Information
Official Symbol
PIK3CA
Officical Full Name
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Primary Source
HGNC:8975
See related
MIM:171834 HPRD:01382
Chromosome Location
3q26.3
Gene Type
protein-coding
Also known as
CLOVE CWS5 MCAP MCM MCMTC PI3K p110-alpha
External Sources
GUDMAP
Experiment Description
Accession
RGED46699
Type
Microarray
Summary
Both cigarette smoking and obesity have been implicated in increased risk of clear cell renal cell carcinoma (ccRCC); however, there are limited data regarding the molecular mechanisms that underlie these associations. We used a multi-stage design to identify and validate specific molecular targets that are associated with smoking or obesity-related ccRCC.The data deposited herein are comprised of two batches of samples that were processed at two different time periods (please see Supplementary Data in Eckel-Passow et al. Carcinogenesis first published online December 28, 2013; doi:10.1093/carcin/bgt485). The first batch of samples consisted of 12 obese subjects and 13 non-obese subjects; all of whom were self-reported never-smokers. Each of the 12 obese subjects had microarray data available on both the patient-matched tumor and adjacent-normal tissues. All of the 13 non-obese subjects had microarray data available on the tumor tissue; however, only 9 of these 13 also had microarray data available on the patient-matched adjacent-normal tissue. The second batch of samples consisted of 16 self-reported smokers and 19 self-reported never smokers; all of whom were non-obese. This second batch of samples also contained 7 subjects who were obese and self-reported smokers. All subjects in the second batch had microarray data available on both the patient-matched tumor and adjacent-normal tissues. Lastly, two of the 13 patients in batch 1 were replicated in batch 2; both were non-obese and a non-smoker.
Experiment Platform
Affymetrix Human Genome U133 Plus 2.0 Array [HG-U133_Plus_2]
Data Source
GSE46699