Description
In this study we tested the ability to predict organ injury from transcriptomics data in Sprague-Dawley rats at early time points after exposure to mercury chloride (10 and 34 hours). We selected mercury chloride, a compound extensively used in animal studies for its ability to cause acute kidney and liver damage.
Overall Design
We treated 30 Sprague-Dawley rats with saline solution (control), 0.25 mg/kg (low dose), and 0.50 mg/kg (high dose) to produce different degrees of injury. RNA samples for gene expression analysis were collected from the kidney at 10 and 34 hours. Number of repicates were five.
Curator
xm_li