RGED RGED / Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice

Public on 2020-12-15

Description

Methods: RNA-seq analysis was performed on mouse kidney samples isolated from female apoEKO mice on 4 diets for 14 weeks: (1) Control diet, (2) control + iodomethylcholine (IMC), Control + IMC. IMC is a TMA-lyase inhibitor to prevent TMA production by gut

Overall Design

mRNA profiles of apoEKO mouse kidneys fed various diets to determine whether a bacterial TMA lyase inhibitor, iodomethylcholine (IMC), can prevent chronic kidney disease induced by adenine feeding.

Curator

xm_li

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