RGED RGED / Deep learning approach identified a gene signature predictive of the severity of renal damage caused by chronic cadmium accumulation

Public on 2021-11-24

Description

Repetitive CdCl2 exposure resulted in cadmium accumulation and remarkable renal injuries in the animals. In the present study, we established an animal model to mimic chronic cadmium exposure-induced renal injury and performed whole transcriptome profiling studies. RNA-Seq data analysis showed that cadmium treatment induced dramatic gene expression changes in kidneys in a dose-dependent manner and higher severity of injury in ob/ob mice.

Overall Design

Kidney mRNA profiles of CdCl2 treated ob/ob (ob) and normal C57BL/6 (b6j) mice

Curator

yq_pan

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