Description
The risk of cardiovascular events rises after acute kidney injury. Leukocytes promote atherosclerotic plaque growth and instability. We here established a model of enhanced remote atherosclerosis after renal ischemia reperfusion injury and investigated the underlying inflammatory mechanisms.
Overall Design
Male LDLr-/- mice were subjected to unilateral ischemia reperfusion (IR) or control (ctrl.) surgery followed by a high fat diet for three or ten weeks.
Curator
yq_pan