Description
Our study reports that CCR2 dependent functional specialization of monocytes into immature macrophages occurs within the TNF-TNFR2 activated vasculature and establishes a chemokine-based autocrine, feed-forward loop that may aplify the inflammation and renal injury.
Overall Design
Nephrotoxic Nephritis induced in 10, eight week old WT mice. Different populations of monocytes were FACS sorted and cells were processed for bulk RNAseq
Curator
yq_pan