RGED RGED / Activation of RXR reprograms chromatin accessibility to protect against acute kidney injury [RNA-seq]

Public on 2022-03-02

Description

Purpose: To explore whether the differences in chromatin openness correlate with distinct gene expression in PTCs of MI and SI; Methods: Proximal tubules were isolated for RNA-seq; Results: Using an optimized data analysis workflow, we mapped reads to the mouse genome (mm10). Approximately 2%-13% of the transcripts showed differential expression within the different groups, with a fold change >= 1.5 and p value <0.05.

Overall Design

RNA-sequencing of different conditions: Sham and bilateral ischemia-reperfusion injury (bIRI) mice with or without bexoratene

Curator

yq_pan

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